Laboratory of Structural Chemistry and Biology
Eötvös Loránd University, Institute of Chemistry, Budapest, Hungary
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Group members
Publications
NMR links
Research areas
BioNMR of peptides and proteins
Design and characterization of
Trp-cage miniproteins
Characterization of
intrinsically disordered proteins
Structure-dynamics-activity studies of the small serine protease inhibitor
SGCI
and related molecules
Generation and analysis of
dynamic structural ensembles
Flexibility analysis of the
CCP1-CCP2 module pair
of human C1r
Location and mode of myosin binding of the
Dynein Light Chain
Protein crystallography
Specificity of
acylpeptide hydrolase
Autoactivation of
C1r
Specificity and autocatalytic activity of
MASP-2
Molecular recognition in
calmodulin-ligand complexes
Crayfish trypsin-SGTI complex
, a high resolution view of the Michaelis complex
Structure, stability and mechanism of action of peptides/proteins by applied quantum chemical methods
Study of enzymatic mechanisms
Structure and stability of α-peptides
Conformational studies
revealing the intrinsic structural preferences of amino acids and peptide building blocks
Conformational dependence of
side-chain protonation properties
of α-amino acids
Chemical shift calculations
to explore structure-chemical shift relationships
β-peptides
Conformational studies
related to an emerging field of synthetic chemistry with potential clinical anf other applications
Computational analysis
of protein structural features
Protein-protein
structure comparison
CCA+:
a program for the analysis of circular dichroism spectra of proteins
